now recommends that people aged 65 years and older, residents in long-term care settings, and people aged 50–64 years with underlying medical conditions should receive a booster shot of Pfizer-BioNTech’s COVID-19 Vaccine at least 6 months after completing their Pfizer-BioNTech primary series. Other groups may receive a booster shot based on their individual risk and benefit. Read’s media statement.

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COVID-19 vaccinesare effective at protecting you from getting sick. Based onwhat we knowabout COVID-19 vaccines, people who have been fully vaccinated candothings that they had stopped doing because of the pandemic.

These recommendations can help you make decisions about daily activities after you are fully vaccinated. Theyarenot intended for healthcare settings.

In general, people are considered fully vaccinated: ±

2 weeks after their second dose in a 2-dose series, such as the Pfizer or Moderna vaccines, or2 weeks after a single-dose vaccine, such as Johnson & Johnson’s Janssen vaccine

If you don’t meet these requirements, regardless of your age, you are NOT fully vaccinated. Keep taking all precautionsuntil you are fully vaccinated.

If you have a condition or are taking medications that weaken your immune system, you may not be fully protected even if you are fully vaccinated. You should continue to take all precautions recommended for unvaccinated people until advised otherwise by your healthcare provider.

People with moderately to severely compromised immune systems should receive an additional doseof mRNA COVID-19 vaccine after the initial 2 doses.

What You Can Do


If you’ve been fully vaccinated:

You can resume activities that you did prior to the pandemic.You need to pay close attention to the situation at your international destinationbefore traveling outside the United States.You do NOT need to get tested before leaving the United States unless your destination requires it.You should still get tested 3-5 days after international travel.You do NOT need to self-quarantine after arriving in the United States.

About the Delta Variant: Vaccines continue to reduce a person’s risk of contracting the virus that cause COVID-19, including this variant. Vaccines are highly effective against severe illness, but the Delta variant causes more infections and spreads faster than earlier forms of the virus that causes COVID-19. Learn more about variants in the US.

What You Should Keep Doing


For now, if you’ve been fully vaccinated:

You will still need to follow guidance at your workplace and local businesses.

What We Know

COVID-19 vaccines are safe and effective at preventing COVID-19, including severe illness and death.COVID-19 vaccines are effective against severe disease and death from variants of the virus that causes COVID-19 currently circulating in the United States, including the Delta variant.Infections happen in only a small proportion of people who are fully vaccinated, even with the Delta variant. When these infections occur among vaccinated people, they tend to be mild.If you are fully vaccinated and become infected with the Delta variant, you can spread the virus to others.People with weakened immune systems, including people who take immunosuppressive medications, may not be protected even if fully vaccinated.

What We’re Still Learning

How longCOVID-19 vaccines can protect people.

Want to learn more about these recommendations? Read our expanded Interim Public Health Recommendations for Fully Vaccinated People.

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± This guidance applies to COVID-19 vaccines currently approved or authorized for emergency use by the U.S. Food and Drug Administration (Pfizer-BioNTech, Moderna, and Johnson & Johnson /Janssen COVID-19 vaccines) and some vaccines used for U.S. participants in COVID-19 vaccine trials (such as Novavax).This guidance can also be applied to COVID-19 vaccines that have been listed for emergency use by the World Health Organization (such as AstraZeneca/Oxford). More information is available at Interim Clinical Considerations for Use of COVID-19 Vaccines |

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Last Updated Sept. 16, 2021
Content source: National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases
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